Louise Victor Lebogne, il primo caso di afasia studiato a fondo, colui che permise il rilevamento e lo studio della cosiddetta “area di Broca” o area del linguaggio parlato.

È proprio Louise Victor Leborgne, un piccolo artigiano parigino, colui che ha reso possibile una delle maggiori scoperte nell’ambito della neuroanatomia moderna. È proprio su di lui, un piccolo artigiano parigino, che lo studioso Paul Broca compì i suoi studi e identificò l’area corticale principale del linguaggio.

“TAN-TAN”: due sillabe ripetute per anni, circa  venti; due sillabe che hanno valso al sig. Leborgne il nomignolo di “paziente tan”; due sillabe, unico modo per esprimersi. Fino a poco tempo fa, si conosceva poco sull’identità di questo misterioso “paziente tan”, tanto presente negli appunti del dottor Broca; oggi, grazie al meticoloso lavoro di  Cezary Domanski dell’Università “Maria Curie-Sklodowska” a Lublino possiamo dire qualcosa in più su colui che, pur inconsapevolmente, ha dato una mano enorme nella comprensione di uno dei meccanismi alla base della nostra vita di relazione.

Louis Leborgne aveva cominciato a manifestare i primi problemi durante la sua giovinezza, periodo caratterizzato da violente crisi di epilessia, ma ciò non gli aveva impedito di svolgere una vita tutto sommato tranquilla, permettendogli di affermarsi come calzolaio a Parigi. Fino al giorno in cui non perse definitivamente la parola. Venne subito ricoverato in ospedale, a causa della sua impossibilità a comunicare: non un ricovero transitorio, ma un ricovero che è durato ben 21 anni, fino alla sua morte.

Inizialmente, si pensò che il suo disturbo fosse collegato alle crisi epilettiche, ma in seguito all’autopsia sul suo cervello effettuata dallo stesso Broca, si mise in evidenza che estese aree corticali erano state danneggiate irrimediabilmente.

Questa scoperta accese la lampadina nella mente di Broca: evidentemente, se queste aree appaiono danneggiate, il soggetto non riesce a parlare.

Dopo numerosi studi, Paul Broca riuscì quindi ad identificare questa zona della corteccia cerebrale, definita appunto area di Broca, localizzata nella parte inferiore della terza circonvoluzione frontale; questa a sua volta può essere suddivisa in due sotto-aree:

  1. pars triangularis (anteriore), associata all’interpretazione di varie modalità di stimoli e alla programmazione dei condotti verbali;
  2. pars opercularis (posteriore), associata a un unico tipo di stimolo e presiede al coordinamento degli organi coinvolti nella riproduzione della parola; essa è fisicamente prossima ad aree del cervello dedicate al controllo dei movimenti.

Un danno di questa area può infatti condurre a forme più o meno gravi di afasia. Ve ne sono di diversi tipi, da quelle fluenti, in cui il soggetto parla ma con notevoli difficoltà nell’uoso di verbi o sotantivi o gravi deficienze grammaticali, a quelle più gravi, in cui il soggetto non parla proprio, passando attraverso la cosiddetta “afasia di Wernicke”, associata all’area uditiva, in cui il soggetto ha problemi nella comprensione del linguaggio e nella sua produzione.

Il cervello di Leborgne è ora conservato nel Musée Dupuytren di Parigi. Analisi recenti hanno evidenziato danni ben più gravi di quelli rilevati da Broca.

Ma ancora una piccola curiosità a proposito del nostro “tan-tan”. L’ipotesi avanzata da Domanski riguardo questa singolare sillaba è successiva, nonché decisamente azzardata: pare sia legata all’infanzia del povero Leborgne, originario della piccola cittadina di Moret-sur-Loigne, paesiano caratteristico per i tipici mulini ad acqua, definiti appunto moulin a tàn.

 

 Fonti |www.lescienze.it

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  106. So, we have actually finally closed the book on 2010.
    Now, as we shift into the new year, this is
    when the majority of people reflect back on the year before.
    In the film world, this is also when critics and film fans make
    the effort to review the past year. Not to mention, this
    is awards season. With the Critics’ Option Awards in just a number of weeks and the Oscars less than two months earlier, suffice to state
    the red carpet is formally out.

    Today, I’m going to toss myself into that really ring as we bring you Lazy-bones Club’s 2010 Motion picture Awards.
    In advance, however, I would like to go on and state, I’m going to
    do this various than those big award shows.

    For one, you’ll see some of the typical categories, but also there will
    be some off-beat ones. Also, call me crazy, however I
    think the biggest factor in judging a movie is its home entertainment worth.
    Given all of the other little elements of making
    a motion picture help to make a movie much better, nevertheless I think home entertainment prospers a motion picture’s
    technical expertise in order to define whether it is good or not.
    So, you won’t be seeing me awarding these
    “artsy” motion pictures just because of their “cinematic accomplishment” (whatever the hell
    that is). Instead, I’ll be evaluating on good ole home entertainment value (with acting,
    story, and so on playing elements).

    So, without more ado, here are the winners of the very first yearly Lazy-bones
    Club Motion Picture Awards.

    Finest Film: Inception

    For me this came down to Inception and Black
    Swan. I’ve truthfully spent days mulling it over in my head which would be my motion picture of the year.
    However, in the end, Beginning wins out. Inceptionwas also perfect
    in a sense. With smart writing, excellent acting, enjoyable action,
    great cinematography and so on and so on, the movie proved to be
    awesome design with excellent compound. Nolan showed once again here why he is one of (if
    not THE) most demanded filmmakers today. A narrative genius.
    After viewing this film, it made me recognize what a god-send Nolan is to Hollywood really.
    Everyone in Hollywood need to be remembering. This is exactly
    how a hit film must be done. Let’s not kid ourselves, hit action motion pictures will continue to be the bread and
    butter of Hollywood for some time to come. While
    this is alright, the problem typically lies in that they’re
    so shallow and cliche and just “eh”. They typically just depend on cool action sequences
    and remarkable looking unique impacts. Not Beginning, though.
    This motion picture provides all that, but then really
    brings substance to that style offering us an engaging and mind-bending/intelligent story to opt for
    it. This best blend makes Beginning my film of the
    year.

    Finest Star: James Franco – 127 Hours

    I’ve said it prior to and I’ll state it once again:
    you want to test the benefit of an actor? Throw him
    in a film where he is practically the only one ever on-screen and he has
    to carry the whole film himself. Where the entire weight of
    the whole movie rests most assuredly on his shoulders.
    Will he shine? Will he collapse? This is the
    test. Others have actually proven themselves in the same way (Will Smith, Tom Hanks).
    And really I believe this (and the “retard function”) is among the greatest
    ways to test an actor and see if he is among the
    greats. So, get in James Franco and 127 Hours. Playing a mountain climber that gets caught under a boulder and is all alone, Franco
    is delegated bring an entire film on his own. Does he prosper?
    Damn right he does. With flying colors at that. Keeping it interesting, communicating a range of
    emotions throughout the film and drawing you in all on his own, Franco clearly shows he had the nerve to take on such an overwhelming task and come out on top.
    For that reason, he’s my actor of the year.

    Best Actress: Natalie Portman – Black Swan

    Natalie’s performance in the Aronofsky psychological thriller is definitely dazzling.
    Her best work to-date in my opinion. Contributing that requires
    her to ultimately shift from sweet little ignorant princess
    lady to girl-gone-wild (in a dark side kinda way), she hits every beat without missing
    an action. I believe the greatest element for a great actor/actress is variety.

    Anyone can shine in a part that was simply made for them (in line with
    their natural persona), however variety and playing different personas/characters is where an actor/actress can show their true prowess.
    In Black Swanalone, Natalie Portman has revealed, in simply the 2 hours, that she has more variety than a lot of starlets around.

    She displayed more range in one efficiency than the
    majority of perform in their entire profession. For such a fantastic performance
    Natalie Portman gets my vote as starlet of the year. I don’t think this is even up for debate.

    Best Supporting Actor: Christian Bale – The Fighter

    Here’s another that I feel is simply a given and isn’t up for dispute.

    Bale absolutely took the show in every scene he appeared in The Fighter The weight reduction alone shows Bale’s commitment to his craft.
    In addition, the way he was able to lose himself in that crackhead persona and into the function of Dicky Eklund
    simply even more showed what a remarkable star Bale is.
    To actually show you how brilliant his performance
    was, the video of real-life Dicky during the credits showed you
    just how well Bale nailed that performance. It had to
    almost resemble searching in a mirror for Dicky.

    Best Supporting Starlet: Melissa Leo – The Fighter.

    Yes, the supporting cast of The Fighter was just fantastic.
    They’re the ones that kept this film afloat. Leo’s turn as the
    “white trash” overbearing mother was great and was another
    (together with Bale’s performance) that actually assisted
    this movie shine. Without these 2, The Fighter bombs.

    Best Director: Darren Aronofsky – Black Swan

    Like I said, best film was down to Black Swan and Creation for me.
    Aronofsky’s work here was damn near best. This was a remarkably directed movie.

    From the video camera shots to the music
    to the story-telling to what he left his cast, Aronofsky did a terrific task in communicating this thriller story really appropriately on all
    levels. As one of my favorite modern directors, it’s no surprise that Aronofsky continues to
    impress every year.

    Finest Screenplay: Mark Heyman, Andres Heinz and John McLaughlin – Black Swan

    For me, screenplay/story is probably the most significant factor
    in figuring out whether a film is entertaining. Afterall, without an interesting and amusing story, then your film is simply going to suck.
    That being said, it’s no surprise that this, for me, came down to Black Swan and Inceptionagain; the two movies vying for my Best Film award.
    However, in the end I need to go with Black Swan edging out in this
    classification. The story was fantastic in my viewpoint.
    Really awesome and appealing story that left you on your seat the whole while through.
    To top it off, though, was all the subtext present throughout
    the film. From the “life mimics art” to the “greed can consume us all” to the commentary of just how much pressure can be placed on a performer and the dangers they occur when losing themselves
    in an efficiency in order to be “ideal”. This script had all of it and fired on a lot of cylinders.
    Really was a great story and I loved how the main character’s life began to mirror the very character she was trying to use stage.

    Finest Ensemble Cast: The Fighter

    I think after the previous supporting awards, this must come as not a surprise.
    However, I will say I was also seriously thinking about The Town for this award which
    had an excellent all-around performance from its whole cast.
    Nevertheless, the cast of The Fighter performed well
    in all areas. Even Mark Wahlberg was good adequate (and I don’t especially care
    for him). Though, he was the weak link and his real character was boring.
    However, everybody else turned in fine performances that, as a whole, truly pulled you into the household in the
    movie. Then the performances of Bale and Leo really just pressed
    the overall ensemble over the top. On The Other Hand,
    Amy Adams delivered a very good efficiency also sticking out.

    Breakout Efficiency of the Year: Jennifer Lawrence – Winter’s Bone

    The motion picture itself, I found was fairly overrated.
    Nevertheless, Jennifer Lawrence in Winter season’s Bone did an absolutely wonderful job of playing the role of Ree Dolly.
    If not for her, the entire motion picture would have been a wash.
    However, her efficiency was very good to watch. It made it even more worthwhile as I got to witness
    that this lady is really a really adept starlet.
    Before this, I had actually just seen her in ‘The Bill Engvall Program’ where she
    plays the normal cliche ditzy teenage girl. Which, honestly,
    there are a million and one women in the nation that might pull that off.
    Seeing her go from that ditzy teen to this gritty and persuading performance was definitely a treat for me and
    revealed me her worth. For that, she gets my Breakout Performance of the Year award.

    Best Action Film: Inception

    Beginning wins here. Of course being my Finest Film
    of the Year, it’s going to likewise win in its particular genre classification. The motion picture fires
    on all cylinders for a practically nonstop joyride, specifically for the
    last half of the movie. The last half specifically, with the
    gun battles and chases after and combats, etc. prove to
    be an adrenalin rush of action. Once again, this is basically the Hollywood-action-blockbuster movie
    perfected.

    Finest Comedy: Get Him to the Greek

    Ok, here’s where some may disagree with me (if they have not already).

    However, it’s my belief that Best Comedy film ought to generally
    be based upon which film was the funniest. Given, there were films I liked
    better general that fall under the comedy classification (Scott
    Pilgrim), but on the laugh scale they didn’t touch Get Him to the Greek.
    Russell Brand name is just humorous. And his part as the common rock star
    was excellent and amusing. Even “P Diddy” (who I hate) had me cracking up throughout this motion picture.

    For me, it truly was the funniest movie of the year.

    Best Cartoon Animation: How to Train Your Dragon

    Yep, I’m doing it. I’m kicking Pixar to the curb this year and letting another person have Finest Animated
    reward. Granted, I actually took pleasure in Toy Story
    3, but for me How to Train Your Dragon was just the
    better motion picture and was more enjoyable. It was cute, amusing, motivating in its own method and refreshing.
    I truly took pleasure in the motion picture. How to Train Your Dragon was among those
    that had heart and depth and was truly stunning (both story-wise and animation).
    One that genuinely appeals to both grownups and kids alike.

    Best Scary Film: Paranormal Activity 2

    I enjoyed the very first one and the follow up shows no different.
    Paranormal Activity has actually been something of a hero for the horror category I think.
    And part 2 makes it a saving grace for Hollywood as the franchise goes
    mainstream. With good pacing and ‘storytelling’, Paranormal Activity 2, like its predecessor, brings the art of stress and suspense back to a relatively burrowed genre.
    It does an excellent job of really getting into
    your imagination and letting it cut loose, in turn intimidating yourself.

    Really a refreshing film in the genre, I can’t await part 3 this fall.

    Best Thriller: The Town

    Yes, I recognize Black Swan is a thriller, and I definitely concur that it’s the much better motion picture.
    However, like the funny motion picture, I feel the Best Thriller film ought to be
    evaluated practically entirely on the “thrill” aspect.
    And while Black Swan did engulf me and keep
    in delighted, The Town pulled that aspect off a bit better.
    Possibly because the action of it dealt with that, I do not know.
    Nevertheless, The Town simply had me truly on the edge of my seat from
    start to finish pretty much. The action was excellent, the film was so intense and the whole of it just never
    ever let up when it took off running, that I could not
    help but be enthralled as I went on that thrill trip.

    Best Docudrama: The Social Network

    Social Networking has been spreading like wildfire in the past years, so it comes as not a surprise that
    it would eventually become the basis of a film.
    The Social media network isn’t simply any movie though.
    Becoming one of the most spoken about films of the year and making a genuine film to be motion picture of the year, the motion picture is a terrific well-rounded movie that everybody must see.
    And it might be among the most significant movies of contemporary (that or its
    equivalent ‘Catfish’).

    Best Indie Movie: Buried

    Another thriller that just keeps you enthralled throughout (yes it
    seems I have a thing for thriller type movies). With such a minimal set and minimal story
    and cast, Buried just seems like it’s set to dissatisfy.
    In spite of all these threats though it manages to prosper and end up being a
    very thrilling and fascinating motion picture, with Reynolds bring it well.

    Finest Fight: Zero-Gravity Corridor Fight – Inception

    The visuals and special effects was simply one element of what made Inception so awesome for me.
    And this fight scene was one of those that stood out above the rest.
    Imaginative, cool to enjoy, action-packed, it actually was just a truly enjoyable
    battle and pretty awesome.

    Tearjerker of the Year: Toy Story 3

    Did I personally weep? No. However, Toy Story 3 I feel is the movie
    of the year that will more than likely make someone cry.
    Possibly it’s the connection after having actually grown up with the series.
    Perhaps it’s simply the depth of emotion developed in some scenes that hit home for most people in a real-life method.
    Whatever it is, Toy Story 3 is sure to get the water supply running for several people.
    With scenes like the incinerator scene and Andy’s last time with the toys (specifically when he recognizes Woody remains in there and he winds up parting with the toy that began it all), Toy Story 3 certainly has its moments
    that truly tug on those heart-strings.

    Finest On-Screen Couple: Ryan Gosling and Michelle Williams – Blue Valentine

    Both of these stars are a few of the better young actors around today (Gosling being my choice
    for finest actor under 30 even). They truly reveal their worth here in this
    motion picture as well. Providing fantastic and powerful efficiencies the two shine on the screen together.
    The chemistry between them is definitely splendid and
    the genuine/real emotion they communicate throughout the film provides for an excellent watch.

    Finest Bad Guy: Gideon Graves (Jason Schwartzman) – Scott Pilgrim vs
    the World

    Jason Schwartzman is simply unconventionally humorous most every time I see him.

    His look in Scott Pilgrim was just icing on the cake for a great motion picture.
    Timeless Schwartzman supplied humor and intelligence to the role, standing out as my favorite villain of a motion picture filled
    with villains.

    Worst Film of the Year: The Last Airbender

    I’m not even going to say anything. Everyone knows it sucks.

    Shyamalan again shows, that in spite of his last film (The Happening being horrible) that he
    can still outshine himself and make a remarkably even worse movie than he ever has.
    The person is spiraling out of control straight down the drain.

    Many Overrated Motion Picture of the Year: The Kids Are All Right

    I’m sorry. It wasn’t that good. The acting was good. Mark Ruffalo was pretty much the conserving grace of the film.

    Other than that the film was so pompous and contrived and just flat out boring.
    Not nearly as good as individuals made it out to be (not even the efficiencies).
    Wasn’t amusing or humorous at all. And the movie absolutely does not
    should have even being thought about as a Best Film
    nominee.

    A Lot Of Underrated Motion Picture of the Year: Kick-Ass

    Sure, the movie got good reviews, even did moderately well
    in its opening weekend. Nevertheless, I feel
    Kick-Ass was simply underappreciated for the year.
    Rather frankly, the motion picture, well … kicked ass.
    In fact, it might decrease as one of my Leading 10 or 15
    favorite films of the year. It’s one of the very best comics adaptations I’ve seen in a long while.

    For me, it was even better than it’s competitorScott Pilgrim.
    A genuinely incredible and enjoyable movie that need to have been given more credit.
    Really entertaining and more people should offer it a shot.

    Best TV Show (Drama): The Walking Dead

    Undoubtedly, my generally TELEVISION show viewing includes sitcoms/comedies.
    However, there are a few dramas I enjoy occasionally. This year’s The Strolling Dead proved to be one of those new shows that drug me in and made me love it.
    Making me eager to see the next season, and dissatisfied I’ll need to wait so long.

    Finest TELEVISION Program (Comedy): Modern Household

    With an amusing ensemble cast and very funny writing, Modern Family has actually proven to be
    one of my preferred brand-new TV shows recently. And with ‘The
    Workplace’ being hit or miss anymore, Modern Familyis
    the one that regularly has me laughing one of the most.
    Most significantly, Eric Stonestreet as “Cam” constantly makes me laugh and
    actually takes the program almost each time he appears.
    His efficiency is what puts this one over the edge for me.
    Though, Big Bang Theory and Jim Parsons efficiency do be available in an extremely
    close 2nd for me.

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